David Dr and Thomas. Gregor Jansen at McGill University in Montreal, have discovered the important role played by an enzyme called ERdj5 inside the cell’s endoplasmic reticulum . The ER works as a sort of packaging plant that folds and prepares proteins for distribution inside or beyond your cell. But when proteins are misfolded in the ER, they need to end up being destroyed in a degradation process – and that is where ERdj5 comes into play.T he acquisition is certainly expected to become neutral to the Company’s fiscal year 2012 earnings, and $0.06 to $0.10 accretive in fiscal 2013.. Celldex fourth one fourth net loss boosts to $12.7 million Celldex Therapeutics, Inc. today reported monetary results for the fourth quarter and the year ended December 31, 2011. Celldex reported a net lack of $12.7 million, or per basic and diluted share, for the fourth quarter of 2011 compared to net income of $22.7 million, or $0.71 basic income per share and $0.70 fully diluted earnings per share, for the fourth quarter of 2010. Net income for the fourth one fourth of 2010 included one-time items totaling $30.5 million for rindopepimut related revenue recorded as a result of the termination of the Pfizer license agreement and a charge to royalty expense related to costs originally capitalized regarding the the Pfizer license agreement.